| Bioactivity | KRAS inhibitor-40 (Compound 41) is a KRAS inhibitor that interferes with the KRAS G12C-BRAF complex. KRAS inhibitor-40 inhibits the ERK phosphorylation of KRAS downstream signaling pathway. KRAS inhibitor-40 can inhibit the proliferation of tumor cells with different KRAS mutation types and has antitumor activity[1]. | 
| CAS | 3059496-56-6 | 
| Formula | C53H68ClF4N9O8S | 
| Molar Mass | 1102.67 | 
| Transport | Room temperature in continental US; may vary elsewhere. | 
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis.  | 
| Reference | [1]. Jianguo Chen, et al. Tricyclic compounds for the treatment of cancer. WO2024208934A1. 2024-10-10. |