| Bioactivity | KRAS inhibitor-31 (compound 33) is a KRAS inhibitor, with KD (SPR) values of 0.019 nM, 0.019 nM and 0.096 nM for KRas G12D, KRas G12C and KRas G12V, respectively[1]. |
| Invitro | KRAS inhibitor-31 (compound 33) 在 Panc08.13、H358 和 SW620 细胞中的 IC50 值分别为 1.1 nM、3.9 nM 和 6.6 nM。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> KRAS inhibitor-31 相关抗体: |
| CAS | 2920695-77-6 |
| Formula | C33H30F3N5O4 |
| Molar Mass | 617.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jacob Cole DEFOREST, et al. Pyrido[4,3-d]pyrimidine compounds. Patent WO2024009191. |
KRAS inhibitor-31
CAS: 2920695-77-6 F: C33H30F3N5O4 W: 617.62
KRAS inhibitor-31 (compound 33) is a KRAS inhibitor, with KD (SPR) values of 0.019 nM, 0.019 nM and 0.096 nM for KRas G1
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