| Bioactivity | KRAS G12C inhibitor 63 (K45) is a | Invitro |
KRAS G12C inhibitor 63 对携带 KRAS-G12C 的 NCI-H23 和 NCI-H358 癌细胞表现出较强的抗增殖能力，IC50 值分别为 0.77 μM 和 1.50 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> KRAS G12C inhibitor 63 相关抗体: |
Formula |
C27H24Cl2N2O4 |
Molar Mass |
511.40 |
Transport |
Room temperature in continental US; may vary elsewhere. |
Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. Reference |
[1]. Shi JT, et al. Discovery of novel coumarin-based KRAS-G12C inhibitors from virtual screening and Rational structural optimization. Bioorg Chem. 2024 Jul;148:107467. |
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