| Bioactivity | KIF18A-IN-14 (Compound Example 81) is a KIF18A inhibitor. KIF18A-IN-14 is available in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit OVCAR-3 cells viability with IC50s of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be used in tumor (e.g. colon, breast, lung) studies[1]. |
| Invitro | EX81-A 和 EX81-B 抑制 OVCAR-3 细胞活力，IC50 分别为 0-0.01 μM 和 0.01-0.1 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> KIF18A-IN-14 相关抗体: |
| CAS | 3051552-75-8 |
| Formula | C26H32F3N5O6S |
| Molar Mass | 599.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ding, et al. Inhibitors of kif18a and uses thereof. WO2024153217.WIPO, 2024-01-19. |
KIF18A-IN-14
CAS: 3051552-75-8 F: C26H32F3N5O6S W: 599.62
KIF18A-IN-14 (Compound Example 81) is a KIF18A inhibitor. KIF18A-IN-14 is available in two forms, EX81-A and its enantio
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