Bioactivity | KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM. | ||||||||||||
Target | IC50: 0.45 μM (KHK) | ||||||||||||
Name | KHK-IN-2 | ||||||||||||
CAS | 2135304-43-5 | ||||||||||||
Formula | C16H19F3N4O3 | ||||||||||||
Molar Mass | 372.34 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Huard K, et al. Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J Med Chem. 2017 Sep 28;60(18):7835-7849. |