PeptideDB

KHK-IN-2

CAS: 2135304-43-5 F: C16H19F3N4O3 W: 372.34

KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM.
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Bioactivity KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM.
Target IC50: 0.45 μM (KHK)
Name KHK-IN-2
CAS 2135304-43-5
Formula C16H19F3N4O3
Molar Mass 372.34
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Huard K, et al. Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J Med Chem. 2017 Sep 28;60(18):7835-7849.