Bioactivity | KGYY15 (Mouse KGYY15) is a CD40 targeting peptide, which weakly inhibits the CD40-CD40L interaction with IC50 of more than 1mM. KGYY15 activates 33% NF-κB pathway at 100 μM[1]. |
CAS | 1690215-31-6 |
Sequence | Val-Leu-Gln-Trp-Ala-Lys-Lys-Gly-Tyr-Tyr-Thr-Met-Lys-Ser-Asn |
Shortening | VLQWAKKGYYTMKSN |
Formula | C84H129N21O22S |
Molar Mass | 1817.12 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bojadzic D, et al., CD40-targeting KGYY15 peptides do not efficiently block the CD40-CD40L interaction. Diabetologia. 2019 Nov;62(11):2158-2160. |