| Bioactivity | KFU-127 (Compound 6b) is a broad spectrum topical antimicrobial capable of one-shot targeting of bacterial and fungal-bacterial biofilms. KFU-127 is considerably toxic for eukaryotic cells[1]. |
| Invitro | KFU-127 (Compound 6b) shows antimycotic activity with MIC values of 0.38, 3.1, 3.1 and 3.1 μg/mL against Candida albicans, Trichophyton rubrum, Aspergillus fumigatus and Fusarium oxysporum, respectively[1].KFU-127 shows antibacterial activity with MIC values of 4, 4, 4 and 16 μg/mL against S. aureus ATCC 29213, B. subtilis 168, S. epidermidis and E. coli MG1655, respectively[1]. |
| Name | KFU-127 |
| Formula | C34H43BrN2O3 |
| Molar Mass | 607.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Garipov MR, et al. Targeting pathogenic fungi, bacteria and fungal-bacterial biofilms by newly synthesized quaternary ammonium derivative of pyridoxine and terbinafine with dual action profile. Bioorg Chem. 2020 Nov;104:104306. |