Bioactivity | KAT modulator-1 (Compound 3) is a KAT modulator. KAT modulator-1 can interact with p300 full-length but not with the catalytic domain. KAT modulator-1 can be used for epigenetics research[1]. | ||||||||||||
Invitro | KAT modulator-1 (Compound 3) (50 μM) 可抑制重组乙酰转移酶 KAT3A 79-83%[1]。KAT modulator-1 (15 和 30 μM) 可降低 U937 白血病细胞组蛋白提取物中的 H3 乙酰化[1]。 0 --> KAT modulator-1 相关抗体: | ||||||||||||
Name | KAT modulator-1 | ||||||||||||
CAS | 1314006-43-3 | ||||||||||||
Formula | C20H36O2 | ||||||||||||
Molar Mass | 308.50 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Milite C, et al. Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs). Bioorg Med Chem. 2011 Jun 15;19(12):3690-701. |