| Bioactivity | K11 is an antimicrobial peptide. K11 is active against MDR/XDR K. pneumoniae isolates (MIC: 8-512 μg/mL), and inhibits bacterial biofilm formation. K11 can act synergistically with antibiotics (Chloramphenicol (HY-B0239), Meropenem (HY-13678), Rifampicin (HY-B0272), etc.) against drug-resistant K. pneumoniae. K11 has high thermal and wide pH stability[1]. |
| Name | K11 |
| CAS | 1398109-79-9 |
| Sequence | Lys-Trp-Lys-Ser-Phe-Ile-Lys-Lys-Leu-Thr-Lys-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-NH2 |
| Shortening | KWKSFIKKLTKKFLHSAKKF-NH2 |
| Formula | C123H198N32O23 |
| Molar Mass | 2493.09 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chatupheeraphat C, et al. Synergistic effect and antibiofilm activity of the antimicrobial peptide K11 with conventional antibiotics against multidrug-resistant and extensively drug-resistant Klebsiella pneumoniae. Front Cell Infect Microbiol. 2023 Apr 11;13:1153868. |