Bioactivity | K-Ras-IN-3 (compound 3) is a potent GDP-KRAS G12V inhibitor with an IC50 value of 0.371 nM. K-Ras-IN-3 has the potential for the research of cancer[1]. |
CAS | 3024991-82-7 |
Formula | C34H29F6N5O4 |
Molar Mass | 685.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Robert B. Kargbo, et al. Innovative Therapeutic Approaches Targeting K-Ras: Analysis of Macrocyclic Compounds, Peptidomimetics, and Pyridopyrimidine Inhibitors, ACS Med. Chem. Lett. 2024, 15, 8, 1196-1198. |