| Bioactivity | Jingzhaotoxin-X (JZTX-X) is a selective Kv4.2 and Kv4.3 potassium channels inhibitor. Jingzhaotoxin-X causes long-lasting mechanical hyperalgesia[1]. |
| Target | Kv4.2, Kv4.3 |
| Name | Jingzhaotoxin-X |
| Sequence | Leu-Cys-Ser-Arg-Glu-Gly-Glu-Phe-Cys-Tyr-Lys-Leu-Arg-Lys-Cys-Cys-Ala-Gly-Phe-Tyr-Cys-Lys-Ala-Phe-Val-Leu-His-Cys-Tyr-Arg-Asn (Disulfide bridge: Cys2-Cys15,Cys9-Cys21,Cys16-Cys28) |
| Shortening | LCSREGEFCYKLRKCCAGFYCKAFVLHCYRN (Disulfide bridge: Cys2-Cys15,Cys9-Cys21,Cys16-Cys28) |
| Formula | C164H242N46O41S6 |
| Molar Mass | 3706.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Deng M, et al. Jingzhaotoxin-X, a gating modifier of Kv4.2 and Kv4.3 potassium channels purified from the venom of the Chinese tarantula Chilobrachys jingzhao. J Venom Anim Toxins Incl Trop Dis. 2020 May 29;26:e20190043. |
Jingzhaotoxin-X
CAS: F: C164H242N46O41S6 W: 3706.35
Jingzhaotoxin-X (JZTX-X) is a selective Kv4.2 and Kv4.3 potassium channels inhibitor. Jingzhaotoxin-X causes long-lastin
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