Bioactivity | Janelia Fluor? 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669?HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1]. Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Storage: protect from light. |
Invitro | JF669 undergoes rapid conversion to thioether product (JF669 displays comparatively excellent photostability, retaining 97% fluorescence after the same number of cycles[1]. |
Name | Janelia Fluor® 669, SE |
CAS | 2127150-20-1 |
Formula | C34H30F3N3O6SSi |
Molar Mass | 693.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jonathan B Grimm, et al. General Synthetic Method for Si-Fluoresceins and Si-Rhodamines. ACS Cent Sci. 2017 Sep 27;3(9):975-985. |