| Bioactivity | Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells[1][2][3]. |
| Invitro | Jagged-1 (188-204) is part of the DSL region, and highly conserved between human Jagged-1 and Jagged-2[2]. |
| Name | Jagged-1 (188-204) |
| CAS | 219127-21-6 |
| Sequence | Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg |
| Shortening | CDDYYYGFGCNKFCRPR |
| Formula | C93H127N25O26S3 |
| Molar Mass | 2107.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |