| Bioactivity | JV-1-36 is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro [1]. |
| Name | JV-1-36 |
| CAS | 221377-79-3 |
| Sequence | {N-(2-phenylacetyl)}-Tyr-{d-Arg}-Asp-Ala-Ile-{4-Cl-Phe}-Thr-Asn-{Har}-{Tyr(Me)}-Arg-Lys-Val-Leu-{Abu}-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-{Nle}-{d-Arg}-{Har}-NH2 |
| Shortening | {N-(2-phenylacetyl)}-Y-{d-Arg}-DAI-{4-Cl-Phe}-TN-{Har}-{Tyr(Me)}-RKVL-{Abu}-QLSARKLLQDI-{Nle}-{d-Arg}-{Har}-NH2 |
| Formula | C172H284ClN53O41 |
| Molar Mass | 3785.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kubra KT, et al. Growth Hormone-Releasing Hormone Antagonist JV-1-36 Suppresses Reactive Oxygen Species Generation in A549 Lung Cancer Cells. Endocrines. 2022 Dec;3(4):813-820. |
JV-1-36
CAS: 221377-79-3 F: C172H284ClN53O41 W: 3785.88
JV-1-36 is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 inhibits the production of reactive oxygen spec
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