Bioactivity | JSH-0009 dimaleate (Compound 1) is a potent CDK9 inhibitor with an IC50 of 0.928 nM. JSH-0009 can effectively inhibit the growth of subcutaneous tumor (cute myelogenous leukemia MV4-11) mice[1]. |
CAS | 2559759-04-3 |
Formula | C33H43ClN6O10S |
Molar Mass | 751.25 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Reference | [1]. Gang Zhou. A kind of novel cell cyclin-dependent kinase CDK9 inhibitor. CN108727363A. |