| Bioactivity | JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1. JS11 ameliorates the pruritus in mouse models[1]. |
| CAS | 1394592-04-1 |
| Formula | C23H28N4O3 |
| Molar Mass | 408.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hoon MA, et al., Compositions and methods for the inhibition of pruritus. WO2019090039. |