| Bioactivity | JS-K is a NO donor that reacts with glutathione to generate NO at physiological pH[1]. JS-K inhibits proliferation, induces apoptosis, and disrupts the cell cycle of Jurkat T acute lymphoblastic leukemia cells[2]. |
| Name | JS-K |
| CAS | 205432-12-8 |
| Formula | C13H16N6O8 |
| Molar Mass | 384.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shami PJ, et al. JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity. Mol Cancer Ther. 2003 Apr;2(4):409-17. |