| Bioactivity | JQ-1 (carboxylic acid)-NH-C2-NH-COOH is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates), which is composed of JQ-1 carboxylic acid (HY-78695) and the corresponding linker: (2-Aminoethyl)carbamic acid (HY-W398806). JQ-1 (carboxylic acid)-NH-C2-NH-COOH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules[1]. |
| Formula | C22H23ClN6O3S |
| Molar Mass | 486.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qian Shao, et al. "Targeted Protein Localization by Covalent 14–3–3 Recruitment." Journal of the American Chemical Society (2024). |
JQ-1 (carboxylic acid)-NH-C2-NH-COOH
CAS: F: C22H23ClN6O3S W: 486.97
JQ-1 (carboxylic acid)-NH-C2-NH-COOH is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates),
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