| Bioactivity | JP-2-249 is a molecular glue that acts as a potent degrader of SMARCA2. JP-2-249 shows decreasing protein level of SMARCA2 in MV-4-11 cells in 1-10 μM[1]. |
| CAS | 3036530-41-0 |
| Formula | C25H25N5O4 |
| Molar Mass | 459.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ethan S Toriki, et al. Rational Chemical Design of Molecular Glue Degraders. ACS Cent Sci. 2023 Apr 11;9(5):915-926. |
JP-2-249
CAS: 3036530-41-0 F: C25H25N5O4 W: 459.50
JP-2-249 is a molecular glue that acts as a potent degrader of SMARCA2. JP-2-249 shows decreasing protein level of SMARC
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