| Bioactivity | JNK-IN-14 is a potent JNK inhibitor with IC| Invitro |
JNK-IN-14 (compound 11e) (2.5-5 μM, 24 h) 在 K562 细胞中以浓度依赖性的方式引起轻微的早期细胞凋亡 (apoptosis)[1]。JNK-IN-14 (1.25-5 μM, 24 h) 与 SP600125 相比，在更高浓度下可以抑制 K562 细胞群，具有更高的抑制能力[1]。 0 --> JNK-IN-14 相关抗体: Apoptosis Analysis Cell Line: |
Name |
JNK-IN-14 |
Formula |
C27H31N5O4S |
Molar Mass |
521.63 |
Transport |
Room temperature in continental US; may vary elsewhere. |
Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. Reference |
[1]. Karim I Mersal, et al. Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.Eur J Med Chem. 2023 Sep 15:261:115779. |
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