| Bioactivity | JNJ-7925476 (hydrochloride) is a triple monoamine uptake inhibitor with the ability to regulate neurotransmitter levels and antidepressant activity. JNJ-7925476 (hydrochloride) can be rapidly absorbed into the plasma in rats, with a higher concentration in the brain than in plasma. It can induce an increase in the levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibits antidepressant activity in the mouse tail suspension test. |
| CAS | 109085-56-5 |
| Formula | C20H20ClN |
| Molar Mass | 309.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor |
JNJ-7925476 hydrochloride
CAS: 109085-56-5 F: C20H20ClN W: 309.83
JNJ-7925476 (hydrochloride) is a triple monoamine uptake inhibitor with the ability to regulate neurotransmitter levels
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