Bioactivity | JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3[1]. |
Name | JNJ-38877605-d1 |
CAS | 1936472-36-4 |
Formula | C19H12DF2N7 |
Molar Mass | 378.36 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sikkema BJ, et al. Quantification and clinical validation of the selective MET kinase inhibitor DO-2 and its metabolites DO-5 and M3 in human plasma. J Pharm Biomed Anal. 2024 Jan 4;240:115962. |