Bioactivity | JNJ-26990990 is a broad-spectrum antiepileptic agent with oral activity. JNJ-26990990 can inhibit voltage-gated Na+ channels and N-type Ca2+ channels, but has a very weak inhibitory effect on human carbonic anhydrase-II (IC50 = 110 μM)[1]. |
CAS | 877316-38-6 |
Formula | C9H10N2O2S2 |
Molar Mass | 242.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Parker MH, et al. Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies. J Med Chem. 2009;52(23):7528-7536. |