| Bioactivity | JNJ-18038683 free base is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively. |
| Target | pKi: 8.19 (rat 5-HT7 receptor), 8.20 (human 5-HT7 receptor). |
| CAS | 851373-91-6 |
| Formula | C20H20ClN3 |
| Molar Mass | 337.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bonaventure P, et al. Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder. J Pharmacol Exp Ther. 2012 Aug;342(2):429-40. |
JNJ-18038683 free base
CAS: 851373-91-6 F: C20H20ClN3 W: 337.85
JNJ-18038683 free base is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and
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