Bioactivity | JNJ-10258859 is a potent and selective phosphodiesterase type 5 inhibitor, with a Ki of 0.23 nM. JNJ-10258859 can be used for erectile dysfunction research[1]. |
Invitro | JNJ-10258859 可有效增强 RFL-6 细胞中 cGMP 的积累,显示出其穿透细胞膜的能力[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> JNJ-10258859 相关抗体: |
CAS | 374927-03-4 |
Formula | C30H24N4O3 |
Molar Mass | 488.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Qiu Y, et al. Characterization of a novel phosphodiesterase type 5 inhibitor: JNJ-10258859. Eur J Pharmacol. 2003 Jul 4;472(1-2):73-80. |