| Bioactivity | JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intake through the interaction of the intestinal endogenous peptide PrRP and the CCK1 receptor. The administration of JMV 236 activates PrRP neurons located in the NTS, thereby enhancing its appetite-suppressing effect. JMV 236 has significant effects on areas of the central nervous system associated with food intake, especially during states of starvation[1]. |
| CAS | 113137-57-8 |
| Sequence | {Boc-Tyr(SO3)}-Nle-Gly-Trp-Nle-Asp-Phe-NH2 |
| Shortening | {Boc-Tyr(SO3)}-{Nle}-GW-{Nle}-DF-NH2 |
| Formula | C56H74N10O18S |
| Molar Mass | 1207.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cholecystokinin system is involved in the anorexigenic effect of peripherally applied palmitoylated prolactin-releasing peptide in fasted mice |
JMV 236
CAS: 113137-57-8 F: C56H74N10O18S W: 1207.31
JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intak
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.