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JMS-175-2

CAS: 3042887-70-4 F: C23H19Cl4N5O3 W: 555.24

JMS-175-2 is a potent agonist of BRCC36 isopeptidase complex (BRISC), with the IC50 of 3.8 μM. JMS-175-2 plays an impor
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Bioactivity JMS-175-2 is a potent agonist of BRCC36 isopeptidase complex (BRISC), with the IC50 of 3.8 μM. JMS-175-2 plays an important role in Type I interferon-mediated diseases[1].
CAS 3042887-70-4
Formula C23H19Cl4N5O3
Molar Mass 555.24
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Reference [1]. "Francesca Chandler, et al. Molecular glues that inhibit specific Zn2+-dependent DUB activity and inflammation. bioRxiv [Preprint]. 2024 Sep 7:2024.09.07.611787."

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Is for research use only, not for human use. We do not sell to patients.