Bioactivity | JG-23 is a 4-chloro modified analog with ability to promote t-tau degradation. JG-23 exhibits good metabolic stability with a long T1/2 value (36 min) in mouse liver microsome assays[1]. |
Name | JG-23 |
CAS | 2640819-75-4 |
Formula | C19H16ClN3OS2 |
Molar Mass | 401.93 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shao H, et al. Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels. Bioorg Med Chem Lett. 2021 Jun 1;41:128025. |