| Bioactivity | JB-95 acetate, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 acetate can selectively disrupt the outer membrane but not the inner membrane of E. coli[1]. |
| Name | JB-95 acetate |
| Sequence | cyclo-(Trp-Arg-Ile-Arg-Ile-{d-Arg}-Trp-Lys-Arg-Leu-Arg-Arg-{d-Pro}-Pro) |
| Shortening | cyclo-(WRIRI-{d-Arg}-WKRLRR-{d-Pro}-P) |
| Formula | C92H151N35O14.xC2H4O2 |
| Molar Mass | 1971.41 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Urfer M, et, al. A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli. J Biol Chem. 2016 Jan 22;291(4):1921-1932. |
JB-95 acetate
CAS: F: C92H151N35O14.xC2H4O2 W: 1971.41 (free base)
JB-95 acetate, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95
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