| Bioactivity | JANEX-1-M is a metabolite of JANEX-1. JANEX-1 is a JAK3 specific inhibitor, which can effectively inhibit mast cell degranulation and the release of pro-inflammatory mediators[1]. |
| CAS | 406484-24-0 |
| Formula | C15H13N3O3 |
| Molar Mass | 283.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Uckun FM, et al. CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation. Drug Metab Dispos. 2002 Jan;30(1):74-85. |
JANEX-1-M
CAS: 406484-24-0 F: C15H13N3O3 W: 283.28
JANEX-1-M is a metabolite of JANEX-1. JANEX-1 is a JAK3 specific inhibitor, which can effectively inhibit mast cell degr
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