| Bioactivity | JAK3/BTK-IN-7 (XL-12) is a JAK3/BTK inhibitor with IC50 values of 2 nM and 14 nM, respectively. JAK3/BTK-IN-7 has anti-inflammatory activity and can be used in the study of rheumatoid arthritis[1]. |
| Target | IC50: 2 nM (JAK3).IC50: 14 nM (BTK). |
| Name | JAK3/BTK-IN-7 |
| CAS | 2844387-16-0 |
| Formula | C29H30N8O4 |
| Molar Mass | 554.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liang T,et al. Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis[J]. Bioorganic & Medicinal Chemistry, 2023: 117354. |
JAK3/BTK-IN-7
CAS: 2844387-16-0 F: C29H30N8O4 W: 554.60
JAK3/BTK-IN-7 (XL-12) is a JAK3/BTK inhibitor with IC50 values of 2 nM and 14 nM, respectively. JAK3/BTK-IN-7 has anti-i
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