| Bioactivity | JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1]. |
| Name | JAK3 covalent inhibitor-1 |
| CAS | 2300106-50-5 |
| Formula | C22H17FN6O2S |
| Molar Mass | 448.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Casimiro-Garcia A, et al. Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J Med Chem. 2018 Dec 13;61(23):10665-10699. |
JAK3 covalent inhibitor-1
CAS: 2300106-50-5 F: C22H17FN6O2S W: 448.47
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and s
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