| Bioactivity | JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with IC50 ≤10 nM against JH2 BIND WT/V617F. JAK2-IN-11 has antitumor activity[1]. |
| CAS | 3057053-17-2 |
| Formula | C31H28D3F3N8O4 |
| Molar Mass | 639.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xin Li, et al. Bicyclic ureas as kinase inhibitors. WO2024191996A1.2024-09-19. |
JAK2-IN-11
CAS: 3057053-17-2 F: C31H28D3F3N8O4 W: 639.64
JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with IC50 ≤10 nM against JH2 BIND WT/V617F. JAK2-IN-11 has antitumor
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