Bioactivity | JAK1-IN-11 (compound 11) is a potent inhibitor of JAK,with IC50s of 0.02 nM (JAK1),and 0.44 nM (JAK2),respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1]. |
Target | IC50: 0.02 nM (JAK1) 和 0.44 nM (JAK2) |
Name | JAK1-IN-11 |
CAS | 2427608-43-1 |
Formula | C26H36N6O4S |
Molar Mass | 528.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shen W. et al. Amide or sulfonamide substituted hydrazine derivative applied as JAK kinase inhibitor. China, CN110724142 A. 2020-01-24. |