| Bioactivity | JAK05 exhibits inhibitory activity against Helicobacter pylori, inhibits strains J63, J196 and J107 with MIC of 3-5 µg/mL. JAK05 exhibits binding affinity to H+/K+-ATPase, COX-1/2, TNF-α and PGE2, reveals antioxidant and anti-inflammatory activities. JAK05 exhibits anti-ulcer activity in rat ethanol-induced gastric ulcer models[1]. |
| Formula | C27H27ClN4O9S |
| Molar Mass | 619.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Azam J, et al., Pharmacological investigation of selected 1,2,4 triazole derivative against ethanol induced gastric ulcer. Bioorg Chem. 2025 Jan;154:108040. |