| Bioactivity | JAK-IN-39 (compound 11) is a JAK inhibitor that suppresses JAK1, JAK2, JAK3 with IC50 values of 0.05, 1.18, and 0.03 nM, respectively. JAK-IN-39 can inhibit the viability of TF-1 cells and also suppress the production of lymphocyte TNFα and INFγ in vitro[1]. |
| CAS | 2250013-34-2 |
| Formula | C25H26N10O2 |
| Molar Mass | 498.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Michal MROCZKIEWICZ, et al. Pyrazole[1,5-a]pyrimidine derivatives as kinase jak inhibitors.WO. WO2018206739A1. 2018-05-10. |
JAK-IN-39
CAS: 2250013-34-2 F: C25H26N10O2 W: 498.54
JAK-IN-39 (compound 11) is a JAK inhibitor that suppresses JAK1, JAK2, JAK3 with IC50 values of 0.05, 1.18, and 0.03 nM,
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