| Bioactivity | JAB-3312 is an orally effective anticancer phosphatase SHP2 inhibitor (IC50: 1.9 nM) with anti-cancer activity. JAB-3312 has good tolerability and significantly induced tumor regression in a KYSE-520 mouse xenograft model[1]. |
| Target | IC50: 1.9 nM (SHP2) |
| CAS | 2245082-05-5 |
| Formula | C21H22ClN7S |
| Molar Mass | 439.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Discovery of JAB-3312, a Potent SHP2 Allosteric Inhibitor for Cancer Treatment |
JAB-3312
CAS: 2245082-05-5 F: C21H22ClN7S W: 439.96
JAB-3312 is an orally effective anticancer phosphatase SHP2 inhibitor (IC50: 1.9 nM) with anti-cancer activity. JAB-3312
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