Bioactivity | J1038 (T 5979345) is a selective HDAC8 inhibitor. J1038 binds the catalytic zinc ion of Schistosoma mansoni HDAC8 (smHDAC8)[1]. |
Target | HDAC8 |
Name | J1038 |
CAS | 949727-86-0 |
Formula | C10H10N2O3S |
Molar Mass | 238.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Marek M, et al. Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni. PLoS Pathog. 2013;9(9):e1003645. |