Bioactivity | J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB1*0401)) and promotes peptide binding to MHC II, which can be used in the study of immune regulation[1]. |
Name | J10-1 |
CAS | 1069110-72-0 |
Formula | C17H9Cl2F3N2O3 |
Molar Mass | 417.17 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Call M J. Small molecule modulators of MHC class II antigen presentation: mechanistic insights and implications for therapeutic application[J]. Molecular Immunology, 2011, 48(15-16): 1735-1743. |