Bioactivity | Izalontamab (SI-B001) is a bispecific anti-EGFR/HER3 monoclonal antibody with high selectivity for EGFR/HER3 heterodimer. Izalontamab can be used for the research of cancer[1]. |
In Vivo | Izalontamab (5-46 mg/kg;静脉注射,每 7 天 1 次,共 4 次) 对不同类型肿瘤显示不同的抗肿瘤疗效[1]。 Animal Model: |
Name | Izalontamab |
CAS | 2559704-24-2 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xue J, et al. Prediction of Human Pharmacokinetics and Clinical Effective Dose of SI-B001, an EGFR/HER3 Bi-specific Monoclonal Antibody. J Pharm Sci. 2020 Oct;109(10):3172-3180. |