Bioactivity | Isozaluzanin C (Dehydrozaluzanin c-derivative) is an anti-inflammatory agent that can be isolated from Saussurea lappa and has immunomodulatory effects. Isozaluzanin C improves tissue damage (lung, kidney, and liver) and excessive inflammation in mice induced by LPS (HY-D1056) or CRKP infection. Isozaluzanin C can be used in the study of bacterial infections and sepsi[1][2]. |
Name | Isozaluzanin C |
CAS | 67667-64-5 |
Formula | C15H18O3 |
Molar Mass | 246.30 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kalsi S,et al. Isodehydrocostus lactone and isozaluzanin C, two guaianolides from Saussurea lappa[J]. Phytochemistry, 1983, 22(9): 1993-1995. [2]. Zou, et al. Dehydrozaluzanin C-derivative protects septic mice by alleviating over-activated inflammatory response and promotes the phagocytosis of macrophages[J]. bioRxiv, 2023: 2023.11. 01.565192. |