| Bioactivity | Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[1][2]. |
| Invitro | Isotretinoin (13-cis-Retinoic acid) may act as a pro-drug that is converted intracellularly to metabolites that are agonists for RAR and RXR nuclear receptors[1].Isotretinoin is highly sensitive to air, heat, and light[3].Isotretinoin (0-40 μM; 24-96 h) significantly inhibits HepG2 cell viability[4].Isotretinoin (10 μM; 48 h) down-regulates c-MYC mRNA expression and this is partially due to P1 or P2 promoter activity[4]. Cell Viability Assay[4] Cell Line: |
| Name | Isotretinoin |
| CAS | 4759-48-2 |
| Formula | C20H28O2 |
| Molar Mass | 300.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light, stored under nitrogen *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |