| Bioactivity | Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis and L. braziliensis. Isonicotinaldehyde 2-pyridin has no significant toxic effects on mouse macrophages. The biological activity of Isonicotinaldehyde 2-pyridin is closely related to increasing reactive oxygen species (ROS) and interfering with parasite mitochondrial function. Isonicotinaldehyde 2-pyridin showed its effects on L. amazonensis in preliminary studies on its pharmacological mechanism of action[1]. |
| CAS | 2241017-37-6 |
| Formula | C11H10N4 |
| Molar Mass | 198.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Synthesis, Biological Activity, and Mechanism of Action of 2-Pyrazyl and Pyridylhydrazone Derivatives, New Classes of Antileishmanial Agents |
Isonicotinaldehyde 2-pyridin
CAS: 2241017-37-6 F: C11H10N4 W: 198.22
Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis a
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