| Bioactivity | Isojacareubin can be isolated from Hypericum japonicum. Isojacareubin covalently inhibits SARS-CoV-2 3CLpro. Isojacareubin also has anti-helicobacter activity. Isojacareubin inhibits PKC, and suppresses hepatocellular carcinoma metastasis and induces apoptosis[1][2][3]. |
| Name | Isojacareubin |
| CAS | 50597-93-8 |
| Formula | C18H14O6 |
| Molar Mass | 326.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kyoko Ishiguro, et al. An isopentenylated flavonol from Hypericum japonicum. Phytochemistry. 1993. 32 (6), 1583-1585. [2]. Khan A, et al. Discovery of Isojacareubin as a covalent inhibitor of SARS-CoV-2 main protease using structural and experimental approaches. J Med Virol. 2023 Feb;95(2):e28542. [3]. Yuan X, et al. Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo. Sci Rep. 2015 Aug 6;5:12889. |
Isojacareubin
CAS: 50597-93-8 F: C18H14O6 W: 326.30
Isojacareubin can be isolated from Hypericum japonicum. Isojacareubin covalently inhibits SARS-CoV-2 3CLpro. Isojacareub
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