| Bioactivity | Isoescin IB is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1]. |
| Invitro | β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response[1]. As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity[1]. |
| Name | Isoescin IB |
| CAS | 219944-46-4 |
| Formula | C55H86O24 |
| Molar Mass | 1131.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |