| Bioactivity | Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A)-induced cardiotoxicity[1]. |
| Invitro | Isodunnianol (10 µM; 6, 24 h) 在 H9C2 细胞中诱导自噬并增加 pAMPK172、pULK1555 的表达，降低 pULK1757、SQSTM2 的表达[1]。 Cell Autophagy Assay[1] Cell Line: |
| Name | Isodunnianol |
| CAS | 139726-30-0 |
| Formula | C27H26O3 |
| Molar Mass | 398.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen C , et al . Isodunnianol alleviates duxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019 May 22;10(5):2651-2657. |
Isodunnianol
CAS: 139726-30-0 F: C27H26O3 W: 398.49
Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,de
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