| Bioactivity | Iroxanadine ((-)-BRX 005) sulfate is a potent activator of p38 kinase, and an enhancer of stress-responsive heat shock protein (Hsp) expression. Iroxanadine sulfate also is a vasculoprotector against atherosclerosis. Iroxanadine sulfate may improve survival of vascular endothelial cells (ECs) following ischemia/reperfusion stress[1]. |
| Invitro | 缺氧前或复氧开始时向培养基中加入 Iroxanadine sulfate (0.1-1 μM) 可显著减少 caspase 依赖性细胞凋亡[1]。 0 --> Iroxanadine sulfate 相关抗体: |
| Name | Iroxanadine sulfate |
| CAS | 276690-61-0 |
| Formula | C14H22N4O5S |
| Molar Mass | 358.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kabakov AE, et al. Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cell Mol Life Sci. 2004 Dec;61(24):3076-86. |
Iroxanadine sulfate
CAS: 276690-61-0 F: C14H22N4O5S W: 358.41
Iroxanadine ((-)-BRX 005) sulfate is a potent activator of p38 kinase, and an enhancer of stress-responsive heat shock p
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