| Bioactivity | Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC50=9.8 μM)[1][2][3]. |
| Invitro | Irisolidone, an isoflavone metabolite, represses JC virus gene expression via inhibition of Sp1 binding in human glial cells[1].Irisolidone can inhibit endothelial cell proliferation[3]. |
| Name | Irisolidone |
| CAS | 2345-17-7 |
| Formula | C17H14O6 |
| Molar Mass | 314.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |