| Bioactivity | Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease[1]. | ||||||||||||
| Invitro | Irbesartan (20 μM, 3 h) reduces Th22 cells chemotaxis in vitro[1].Irbesartan (0 μM, 20 μM, 40 μM and 60 μM) suppresses Th22 cells differentiation in vitro[1].Irbesartan (20 μM) inhibits Th22 cells related proinflammatory response of TECs in vitro[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | Irbesartan | ||||||||||||
| CAS | 138402-11-6 | ||||||||||||
| Formula | C25H28N6O | ||||||||||||
| Molar Mass | 428.53 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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