| Bioactivity | Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease[1]. |
| Invitro | Irbesartan hydrochloride (20 μM, 3 h) reduces Th22 cells chemotaxis in vitro[1].Irbesartan hydrochloride (0 μM, 20 μM, 40 μM and 60 μM) suppresses Th22 cells differentiation in vitro[1].Irbesartan hydrochloride (20 μM) inhibits Th22 cells related proinflammatory response of TECs in vitro[1]. Cell Viability Assay[1] Cell Line: |
| Name | Irbesartan hydrochloride |
| CAS | 329055-23-4 |
| Formula | C25H29ClN6O |
| Molar Mass | 464.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |